Emphysematous pyelonephritis and diabetes mellitus: A clinical perspective

Charan Bale; Sunil Mhaske; Vedavati B Purandare; Akshay Kulkarni; Abhijit Chavan; Nishant Vyas; Bharat Purandare

doi:10.4103/cdrp.cdrp_CDRP_12_22

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Year : 2023 \| Volume : 2 \| Issue : 1 \| Page : 46-53

Emphysematous pyelonephritis and diabetes mellitus: A clinical perspective Charan Bale¹, Sunil Mhaske², Vedavati B Purandare³, Akshay Kulkarni⁴, Abhijit Chavan⁴, Nishant Vyas⁵, Bharat Purandare⁶ ¹ Department of Nephrology, Dr. D. Y. Patil Medical College, Hospital and Research Center, Pune, Maharashtra, India ² Department of Urology, Dr. D.Y. Patil Medical College and Research Hospital, DPU, Pune, Maharashtra, India ³ Department of Medicine, Chellaram Diabetes Institute, Pune, Maharashtra, India ⁴ Department of Nephrology, Dr. D. Y. Patil Medical College and Research Centre, D. Y. Patil Vidyapeeth, Pune, Maharashtra, India ⁵ Department of Immunology, Logical Life Sciences Pvt. Ltd., Pune, Maharashtra, India ⁶ Department of Infectious Disease, Deenanath Mangeshkar Hospital and Research Center, Pune, Maharashtra, India Correspondence Address: Charan Bale Dr. D. Y. Patil Medical College and Research Centre, Pune, Maharashtra India Source of Support: None, Conflict of Interest: None DOI: 10.4103/cdrp.cdrp_CDRP_12_22

Emphysematous urinary tract infections (UTIs) are lower or upper UTIs associated with gas formation. Emphysematous pyelonephritis (EPN) is a rare disease but is highly prevalent in patients with diabetes and even higher among female patients with diabetes. Earlier, the mortality rate of EPN was 60%–80%, but now, it has been reduced to 20% to 25% due to the availability of good antimicrobial agents and timely treatment. Our objective of this article is to elucidate the pathogenesis of EPN including gas-forming mechanism; discuss clinical features, radiological classification, and prognostic factors; in addition, compare the modalities of management of EPN and outcome among the various radiological classes.



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